单词 excitotoxicity 释义 BETA

Examples ofexcitotoxicity

Dictionary> Examples ofexcitotoxicityexcitotoxicityisn’t in the Cambridge Dictionary yet. You can help!Add a definitionNeuronal injury in the cell cultures resulting from glutamateexcitotoxicityis assessed by quantifying the release of lactate dehydrogenase into the culture medium.From theCambridge English CorpusResearch into pathogenesis has shed light on the possible mechanisms of injury, which include mechanical, vascular, immunological andexcitotoxicity.From theCambridge English CorpusThese results show that l-glutamate can be used as an excitotoxic agent to eliminate cholinergic amacrine cells, but that thisexcitotoxicityis not selective.From theCambridge English CorpusOne of the functions of membrane-associated glutamate transpor ters which has received considerable attention is that of preventingexcitotoxicity.From theCambridge English CorpusGlutamateexcitotoxicitycontributes to oligodendrocytes death and myelin loss in multiple sclerosis and other neurodegenerative conditions.From theCambridge English CorpusTogether these findings provide insights into how activation of microglia alters glutamate homeostasis, which results in oligodendrocyteexcitotoxicity.From theCambridge English CorpusExcitotoxicityappears to play a role in both neurodegenerative and cerebrovascular diseases.From theCambridge English CorpusTherapies designed to directly abrogate neuronalexcitotoxicitymight also prove to be advantageous.From theCambridge English CorpusThe molecular pathways that underlie these mechanisms might be important in protecting againstexcitotoxicity.From theCambridge English CorpusAn experimental basis for implicatingexcitotoxicityin glaucomatous optic neuropathy.From theCambridge English CorpusFurthermore, the continual activation of high frequency cortical areas through the "edge effect" provides a framework for the development ofexcitotoxicityof cortical cells.From theCambridge English CorpusFurthermore, the continuous high frequency cortical activation due to the edge effect provides a framework for the development ofexcitotoxicityof cortical cells.From theCambridge English CorpusIt is likely that inflammation andexcitotoxicitytogether contribute to neuronal damage beyond the initial insult of acute trauma.From theCambridge English CorpusSeveral other trials of agents targeted against glutamateexcitotoxicityhave sadly been disappointing.From theCambridge English CorpusWe believe that there is enough precedent to believe that these questions will lead to a uniquely useful view of the underlying mechanisms ofexcitotoxicity.From theCambridge English CorpusThis increase was predominantly due toexcitotoxicityas well as oxidative stress.From theCambridge English CorpusIf initial responses of receptor desensitization and more inhibitory receptors are not sufficient to control overactivity, thenexcitotoxicityis likely.From theCambridge English Corpus

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